Anti-human TNFRSF9/4-1BB monoclonal antibody, utomilumab biosimilar (PF-05082566, PF-2566)

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PRODUCT

  • SKU

    DMS1175-100ug

  • Size

    100 ug

  • Price

    $350

1
This monoclonal antibody is part of a collection of biosimilar antibodies in reference to those approved or in clinical investigation. The biosimilars are for Research Use Only and should not be used in therapeutic or diagnostic procedures in humans or animals.
target TNFRSF9
alias TNFRSF9, 4-1BB, CD137, CDw137, ILA
gene id Uniprote ID: Q07011
host species Human
reactivity Human
iso type IgG2
formulation Lyophilized from sterile PBS, pH 7.4. Typically, 5% - 8% trehalose is added as a protective agent prior to lyophilization.
reconstitution Reconstitute lyophilized powder with water to a concentration of 100 ug/ml, solubilize at RT for 30 minutes with occasional gentle tapping. It is recommended that 0.1% HSA be added as a carrier protein for long-term storage.
applications ELISA; Flow Cytometry
dilution ELISA 1:5000-10000
shipping Shipped at ambient conditions.
storage Lyophilized form is stable for 1 week at room temperature. Store at -20 °C to -80 °C for 12 months in lyophilized form. After reconstitution, store at 4 °C for 2-7 days or at below -20 °C for up to 3 months.
note Other commonly used names in publications refering to this antibody: PF-05082566, PF-2566

Images

Flow cytometry analysis of anti-4-1BB (utomilumab) on Expi293 cells transfected with human 4-1BB (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).

ELISA plate coated with 2 ug/ml (100 ul/well) Human 4-1BB, mFc-His tagged protein binds to anti-4-1BB neutralizing antibody in a linear range of 3.2-400 ng/ml.


PRODUCT

  • SKU

    DMS1175-100ug

  • Size

    100 ug

  • Price

    $350

1