Anti-human CD274/PDL1 monoclonal antibody, durvalumab biosimilar (MEDI4736)

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PRODUCT

  • SKU

    DMS1028-100ug

  • Size

    100 ug

  • Price

    $350

1
This monoclonal antibody is part of a collection of biosimilar antibodies in reference to those approved or in clinical investigation. The biosimilars are for Research Use Only and should not be used in therapeutic or diagnostic procedures in humans or animals.
target CD274
alias PD-L1, CD274, B7-H1, PDCD1L1, PDCD1LG1
gene id Uniprote ID: Q9NZQ7
host species Humanized
reactivity Human
iso type IgG1(K97R, L117F, L118E, P214S)
formulation Lyophilized from sterile PBS, pH 7.4. Typically, 5% - 8% trehalose is added as a protective agent prior to lyophilization.
reconstitution Reconstitute lyophilized powder with water to a concentration of 100 ug/ml, solubilize at RT for 30 minutes with occasional gentle tapping. It is recommended that 0.1% HSA be added as a carrier protein for long-term storage.
applications Flow Cytometry
dilution Flow Cyt 1:100
shipping Shipped at ambient conditions.
storage Lyophilized form is stable for 1 week at room temperature. Store at -20 °C to -80 °C for 12 months in lyophilized form. After reconstitution, store at 4 °C for 2-7 days or at below -20 °C for up to 3 months.
note Other commonly used names in publications refering to this antibody: MEDI4736

Images

ELISA plate coated with 2 ug/ml (100 ul/well) Human PDL1, mFc-His tagged protein binds to anti-PDL1 (durvalumab biosimilar) neutralizing antibody in a linear range of 0.61-9.77 ng/ml.

Flow cytometry analysis of 1 ug/mL anti-PDL1 (durvalumab biosimilar) mAb on Expi293 cells transfected with Human PDL1 protein (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).


PRODUCT

  • SKU

    DMS1028-100ug

  • Size

    100 ug

  • Price

    $350

1